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Science  24 Dec 2010:
Vol. 330, Issue 6012, pp. 1839
DOI: 10.1126/science.330.6012.1839-a

Hplc Columns

The new Syncronis range of high-performance liquid chromatography (HPLC) columns unerringly delivers consistent, predictable separations, from run to run and column to column. When developing a new method, one of the key goals for the chromatographer is to achieve a consistent, reproducible separation. The selection of a highly reproducible HPLC column is essential to attaining this goal. The new Syncronis column range has been engineered to deliver exceptional reproducibility by providing highly pure, high surface-area silica, dense bonding, and double endcapping, all controlled and characterized through rigorous testing. New enhanced, automated column packing methods used within the Syncronis range deliver greater consistency, and every column is individually tested to ensure that it meets the required specifications. These extensive testing and quality control procedures ensure the delivery of a completely consistent product, column after column. Syncronis columns are available with 5 μm particle size for conventional HPLC applications and with 1.7 μm particle size for high-speed, high-efficiency UHPLC separations.

Pressure/Flow Rate Sensors

The new Mitos Sensor Units provide a flexible system for measuring and displaying pressure and flow rates in microfluidic systems. With a real-time display and low internal volumes, each sensor is designed to minimize interference with the liquid flow. All data is clearly displayed on the Mitos Sensor Display unit, which interfaces with each of the sensor units using a simple push-and-click action. Comprising five flow rate sensors and one pressure sensor (-0.5–30 bar), the complete range is fully interchangeable and each device can run stand-alone or integrated with a Mitos P-Pump for the efficient logging of flow rate output. All data is easily transferrable to a PC for further analysis via USB. Ongoing enhancements to the system will soon enable the flow rate sensors to communicate with the Mitos P-Pump to create a closed loop pumping system. This will enable the user to automatically control flow rates using pressure, providing the ultimate in smooth liquid flow.

Controlled Rate Freezer

The Bio-Cool is the only controlled rate freezer that does not require expendable liquid nitrogen and the associated pumping, refilling, and storage challenges posed by a cryogenic liquid. The Bio-Cool, simply plugs into a standard electrical outlet and quietly provides low temperature cooling to either -40°C or -80°C. Unlike liquid nitrogen systems, which surround samples with a cold vapor phase, the Bio-Cool immerses samples into a well-circulated, cold liquid bath. The circulating liquid allows more efficient heat transfer to the samples and maintains a more consistent temperature profile at all locations. The Bio-Cool comes standard with an easy-to-use programmable microprocessor controller that enables programming and storage of up to eight different protocols, each with up to eight distinct segments specifying ramp rate, hold temperature, and hold time. Elimination of liquid nitrogen handling and usage, better freezing results, simple straightforward operation, and world-class service support all make the Bio-Cool the controlled rate freezer of choice for most clinical, commercial, and research applications.

Imaging Camera

Engineered for high-sensitivity and high-speed performance in low-light imaging applications, the Rolera EM-C2 camera aids researchers in applications such as spinning-disc confocal imaging, total internal reflection fluorescence (TIRF) microscopy, ratiometric ion imaging, and fluorescence recovery after photobleaching (FRAP). Fast frame rates essential to cutting-edge live cell imaging studies are enabled by the camera's 40 MHz pixel clock rate. Up to 34.2 full-resolution (one megapixel) frames per second can be read out and transferred over an optimized 800 Mb/s implementation of the IEEE 1394b FireWire protocol. The Rolera EM-C2 delivers very low noise and high-sensitivity across a broad spectrum common to fluorescence experiments. This camera introduces an Easy-EM mode, which optimizes camera EM Gain settings with a single click. Researchers no longer have to gauge sensitivity using the arbitrary sliders that are required with the use of existing cameras to estimate necessary EM Gain. The camera includes the QCapture Suite software, which can be installed and operational within minutes.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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