Lessons from Genomics

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Science  04 Feb 2011:
Vol. 331, Issue 6017, pp. 511
DOI: 10.1126/science.1203356

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In February 2001, Nature and Science provided the first detailed look at the human genome: a string of some 3 billion nucleotides whose unique sequence forms the genetic blueprint for each individual. This momentous occasion made headlines around the world. Now that a decade has elapsed, where has this achievement led us and where are we going with other such ambitious endeavors? Throughout this month in Science, the News and Commentary sections will present viewpoints and analyses of the effects of the genomics revolution on science and society (see http://scim.ag/genome10). Many lessons can be derived from the Human Genome Project that should be helpful in guiding other large science projects through their inevitable challenges.*