News & AnalysisEndocrinology

Mice Prompt Look at Cholesterol's Role in Female Fertility

Science  10 Jun 2011:
Vol. 332, Issue 6035, pp. 1252-1253
DOI: 10.1126/science.332.6035.1252

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It's easy to forget that cholesterol isn't simply a villain. The white, waxy substance is famously intertwined with heart disease, but cholesterol lives all over the body, building cell membranes and hormones. A small group of researchers is now wondering whether cholesterol also helps maintain fertility—and whether cholesterol abnormalities impair a woman's ability to get and stay pregnant. There's even speculation that a cholesterol-lowering drug, which is no longer on the market, could treat a subset of women who are battling infertility.