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Science  10 Jun 2011:
Vol. 332, Issue 6035, pp. 1333
DOI: 10.1126/science.332.6035.1333-a

Gel Electrophoresis ANALYSIS

QIAGEN's ScreenGel software enables the convenient DNA fragment and RNA analysis with the QIAxcel multicapillary gel electrophoresis systems. It combines the highest possible flexibility for researchers with the ability for standardized and reproducible operations in routine labs. ScreenGel allows easy performance, interpretation, and customized documentation of electrophoresis analysis with an intuitive user interface. The software also supports electronic record requirements specified under 21 CFR part 11, and enables standardized sample processing with process templates as well as secure user management with a variety of access levels. The software is launched together with the new QIAxcel Advanced system, which comes with improved hardware features and a new look and feel. The system enables effortless automated electrophoresis, which replaces traditional labor-intensive gel analysis of DNA and RNA, streamlines the workflow and significantly reduces time to result.

Chimerism Analysis

The new automated chimerism software, ChimerMarker, integrates the previously distinct analysis operations for initial donor/recipient compatibility and post-engraftment longitudinal studies. The new software, compatible with outputs from all major capillary electrophoresis platforms as well as commercially available STR and custom chemistries, integrates sizing and allele calling with automated chimerism analysis, eliminating the need for tedious and error-prone data transfer which is today's norm. ChimerMarker software can be used to monitor chimerism in both allogeneic and autologous stem cell transplant, hematopoietic stem cell transplant, bone marrow transplant, and peripheral blood stem cell transplant. The program preferences include labeling of peak ratios by height or area, with multilineage capabilities for chimerism analysis of T cells, B cells, and other cell type populations, which may indicate graft-versus-host disease or graft rejection. Case-specific panels are automatically constructed using donor recipient allele calls.

Pipette Management

Version 3 of the Pipette TrackerT software is tightly integrated with the Artel PCS (Pipette Calibration System), providing a total management system for quality control of any pipette population. The updated software brings even more convenience to laboratories by proactively notifying quality control managers and laboratory technicians through e-mail when pipettes are due for calibration and/or preventive maintenance. Pipette Tracker software provides more tools to analyze pipette calibration and maintenance records, making it easy to identify poor performance trends early on. The software allows laboratories to set action limits, which will alert users when a pipette is nearing its individual performance specifications, allowing preventive maintenance to be performed before pipette failure occurs. This version also maintains information on each preventive maintenance or repair event, allowing the laboratory to generate a complete history of calibration and maintenance data for each pipette and receive early warnings if a pipette approaches its tolerance limits.

Laboratory Information Management System

The enhanced Qualoupe Laboratory Information Management System (LIMS) software features a simple-to-use, intuitive user interface that offers both clarity and flexibility never before seen in the commercial LIMS industry. The specially optimized software ensures that user interface functions assist users to work simply, clearly, and efficiently in the way they wish to work. A case in point is the way that Qualoupe's roles functionality has been designed to modify the users interface to reflect the LIMS capabilities assigned to the users role. Another popular user interface feature offered by the latest release of Qualoupe allows users to define sequential sample numbering by laboratory, by batch, or by project. The web-based Qualoupe user-customizable interface is principally icon-driven and features uncluttered screens using a Just Enough Information Model (JEIM) that requires minimal mouse clicks to operate.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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