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Comment on “Additive Genetic Breeding Values Correlate with the Load of Partially Deleterious Mutations”

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Science  02 Sep 2011:
Vol. 333, Issue 6047, pp. 1221
DOI: 10.1126/science.1200996

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Abstract

Tomkins et al. (Reports, 14 May 2010, p. 892) reported a strong negative correlation between breeding values and mutational load in cow-pea weevils. Here, I show that this result can be attributed to a statistical artifact. By testing the observed correlation against an incorrect null hypothesis, they find a negative correlation where one does not exist.

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