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Science  23 Sep 2011:
Vol. 333, Issue 6050, pp. 1770
DOI: 10.1126/science.333.6050.1770-a

Chemiluminescent Imaging System

The new GeneGnome5 is a dedicated chemiluminescent imaging system designed to make precise imaging of chemiluminescent Western blots a simple, one-click task. The GeneGnome5 has a high resolution, cooled camera inside a light-tight cabinet that is fully integrated with a processor and flat screen monitor. The GeneGnome5 is quick and easy to set up as its fixed aperture lens means scientists don't need to spend time adjusting the camera and they can load blots into the system's slide-out drawer, view the image, and capture it with just one click. The GeneGnome5, which includes a white light for viewing colored protein markers, generates images using Syngene's new GeneSys image capture software. This unique software automatically selects the best conditions for imaging any blot, regardless of which chemiluminescent reagents scientists are using, to produce a high-quality image from even poorly expressed proteins.

Nanoscale Protein Analysis

The NanoArray Assay System is based on tip-based Dip Pen Nanolithography technology, which can create highly reproducible protein arrays over millimeter areas with nanometer precision and then fluorescently image these nanoarrays at high resolution. Components of the NanoArray Assay System include the NanoArrayer 3000, the NanoScan 900 scanner, and user-friendly software for flexible and precise array patterning and intuitive data acquisition and image analysis. The NanoArrayer 3000 is capable of depositing thousands of uniform protein features in the area occupied by just one spot on a conventional protein microarray. This miniaturization and precision enables high throughput protein analysis on a single slide. Miniaturized and multiplexed NanoArray Assay System assays achieve femtograms/milliliter sensitivity with 2 μL of sample, comparable to or better than the sensitivities of enzyme-linked immunosorbent assay and bead-based assays that consume 50 μL of sample.

Deep-Well Microplate Washer

The new ELx405 Select Deep-Well Washer is a robot compatible, full plate washer for automated aspirate and dispense steps in 96- and 384-well plates up to 50 mm high, and can also accommodate standard 15 mm microplates. This delivers increased washing efficiency compared to manual and handheld methods. The ELx405 Select Deep-Well Washer also features a dual-action manifold for independent and precise aspirate/dispense control, and variable flow rates and angled dispensing for optimized cell washing. Washing protocols may be created and run through the familiar keypad interface or through BioTek's Liquid Handling Control (LHC) Software. Additionally, optional Ultrasonic Advantage integrated ultrasonic cleaners provide manifold self-maintenance, and optional automatic 1-to-4 wash buffer switching further enhances efficiency. Typical applications that can now be automated include: plasmid DNA purification, serum/plasma sample preparation, hematopoietic progenitor cell enumeration, and cell proliferation assays.

  • BioTek Instruments

  • For info: 888-451-5171


Manual Micropipettes

The new Socorex Acura manual 826 XS micropipette line is designed to improve a researcher's ability to aim, especially when working with smaller openings such as microtubes. The micropipette is intentionally shorter in design, featuring an optimized shape-to-size ratio that facilitates superior drivability of the pipette and significantly improves the precision of hand movement when pipetting into small vials and microtubes. The unique tightness lip seal reduces activation forces and provides for ultrasoft pipetting, greatly reducing hand-fatigue while working. Sharp plunger stops result in unsurpassed metrological performance. The micropipette's Justip height-adjustment system permits for the optimal fitting and ejection of a wide selection of tips, and tip ejection becomes easier than ever due to the low-pressure activation button. Tedious calibration procedures become obsolete with its swift-set user calibration system and integrated key and locking mechanism.

Acid Resistant Evaporator

The EZ-2 HCl evaporator uses inert and corrosion-proof materials to enable it to withstand high concentrations of up to 12 molar hydrochloric acid and other acid chlorides. These can be routinely removed from samples without any loss of performance or long-term deterioration in the system. Acid resistant components in the EZ-2 HCl include a PTFE-coated evaporation chamber and a glass condenser. All metallic parts coming into contact with removed solvent are manufactured from acid resistant Hasteloy C steel. The innovative design of the EZ-2 HCl presents real advantages for all chemists faced with removing both regular solvents and strongly acidic chemicals. Intuitive controls and large LCD display provide ease of use comparable to a typical rotary evaporator, yet the EZ-2 HCl can process many more samples per unit time. Smart evaporator software provides true walkaway automation so simple and sample-safe that anyone can use it with confidence.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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