News & AnalysisSTEM CELLS

Human Cells Cloned—Almost

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Science  07 Oct 2011:
Vol. 334, Issue 6052, pp. 26-27
DOI: 10.1126/science.334.6052.26

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It's a result many have hoped for—and some have feared—for more than a decade: Researchers have found a way to use human oocytes to reprogram adult cells, allowing them to form early embryos that can give rise to embryonic stem cells. The resulting stem cells are not normal, however. They carry the genomes of both the adult cell and the oocyte, so they have three copies of each chromosome instead of the usual two. But they can still form a variety of tissues in the lab, and they seem, in initial tests, to act like other pluripotent stem cells, cells that can form all of the body's tissue types.