News & AnalysisMalaria

Vaccine Trial Meets Modest Expectations, Buoys Hopes

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Science  21 Oct 2011:
Vol. 334, Issue 6054, pp. 298-299
DOI: 10.1126/science.334.6054.298

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Initial, eagerly awaited results from the world's first large-scale trial of a malaria vaccine, carried out at 11 sites in seven African countries, show that it reduced episodes of the disease by about half in babies and toddlers. That confirms the efficacy seen in earlier, much smaller trials of the experimental vaccine, so far the only one to show significant benefit against malaria in real-world settings. The new findings keep the candidate on track to become the first licensed vaccine against the disease, malaria vaccine experts say.