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Transgenerational Epigenetic Instability Is a Source of Novel Methylation Variants

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Science  21 Oct 2011:
Vol. 334, Issue 6054, pp. 369-373
DOI: 10.1126/science.1212959

Article Information

vol. 334 no. 6054 369-373

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History: 
  • Received for publication August 22, 2011
  • Accepted for publication September 7, 2011

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Author Information

  1. Robert J. Schmitz1,2,
  2. Matthew D. Schultz1,2,3,
  3. Mathew G. Lewsey1,2,
  4. Ronan C. O’Malley2,
  5. Mark A. Urich1,2,
  6. Ondrej Libiger4,
  7. Nicholas J. Schork4,
  8. Joseph R. Ecker1,2,5,*
  1. 1Plant Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  2. 2Genomic Analysis Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  3. 3Bioinformatics Program, University of California at San Diego, La Jolla, CA 92093, USA.
  4. 4The Scripps Translational Science Institute and the Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA.
  5. 5Howard Hughes Medical Institute, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
  1. *To whom the correspondence should be addressed. E-mail: ecker{at}salk.edu

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