New Products

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Science  09 Dec 2011:
Vol. 334, Issue 6061, pp. 1432
DOI: 10.1126/science.334.6061.1432-a

Automated Liquid Handler

The CV2000 automated aliquoting liquid handler is a second-generation platform that enhances laboratory efficiency through workflow automation. The system can accurately dispense liquid volumes from 100 to 875 μL and process up to 1,000 samples per hour. With its robotic arm and rotary height sensors, it fits easily into automated workflows to boost sample throughput. The system is compatible with a wide variety of sample management software, but can also be used as a stand-alone instrument. The system effectively manages samples to boost efficiency and productivity with zero cross-contamination. Fully compatible with multiple rack formats, the CV2000 system allows users to change the loading and dispensing routine to suit their needs. A unique tip preservation system allows the instrument to only discharge used tips, reducing waste while eliminating contamination.

Preclinical Imaging System

The IVIS Spectrum CT is a breakthrough preclinical imaging system that integrates advanced optical imaging and low dose microCT (microcomputed tomography) into a single instrument system. Spectrum CT enables simultaneous molecular and anatomical longitudinal studies, providing researchers with vital, unparalleled insights into complex biological systems in small animal models used to develop new, clinically translatable discoveries. A broad array of applications exist for the new instrument, with musculoskeletal, vascular, cardiovascular, and respiratory disease, as well as oncology and phenotyping, among those areas particularly enabled by the integration of optical and microCT imaging. The system's features include optical sensitivity capable of achieving detection of a few cells and three-dimensional reconstructions of optical molecular bioluminescence and fluorescence signals, integrated with three-dimensional anatomical microCT images. Designed for high throughput, quantitative, noninvasive longitudinal analysis of large cohorts of animals, Spectrum CT enables new, clinically translatable insights.

Transfection Reagent

GeneIn is a new transfection reagent specifically designed to transfect stem cells and primary cells. Stem cells and primary cells have traditionally proven to be very difficult to transfect. Comparative studies against other commercially available reagents show GeneIn to be superior in transfection efficiency with minimum cytotoxicity. GeneIn is a novel cationic transfection reagent formulated from proprietary compounds that are chemically defined and are of animal-free origin. Tested on a wide range of commonly used cell lines and operating over a wide dynamic range, GeneIn offers minimal optimization to achieve superior expression results. GeneIn transfection reagent is part of a range of stem-cell qualified products that offer reproducible performance and high consistency from lot to lot.

Digital Imaging Camera

The new, easy-to-use SC100 digital color camera is designed for high-quality brightfield imaging, especially where optimal color reproduction and superior resolution are required. The 10.5 megapixel sensor of the SC100 allows samples to be investigated in minute detail, particularly when using a low-magnification objective. This frees users from needing to take multiple, high-magnification images of a sample to preserve resolution. Similarly, images can be easily investigated at high digital magnification at a later date, even if this was not initially intended when using a low-magnification objective. Thus the SC100 is perfect for intensive documentation and makes it easy to analyze samples in detail, at a convenient time for the user and without losing sight of the bigger picture. The SC100 digital color camera can capture in-depth image details in a single shot, without the use of any pixel-shift technology.

Autophagy Biomarker Kits

The new p62 and NBR1 ELISA kits enable quantitative measurement of autophagy biomarkers without the need for expensive equipment or long procedures. The p62 (sequestosome 1) and NBR1 ELISA kits provide a quantitative, immunometric detection method for measuring autophagy in human, rat, and mouse cell lysates. These sensitive assays measure as little as 66 or 100 pg/mL of NBR1 or p62, respectively, and provide fully quantitative results that surpass semiquantitative Western blot analysis. With the ability to analyze up to 40 samples in duplicate in less than three hours, these kits meet the need for rapid, high throughput analysis. They are supplied with an easy-to-follow protocol, precoated microtiter plate, and liquid color-coded reagents to save the user time and reduce errors. The break-a-part strip plate design provides flexibility, and means not having to run all 96 wells at once. Each kit is put through rigorous fit-for-purpose validation and stability testing to ensure high precision, accuracy, sensitivity, and specificity.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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