Sensible Balance

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Science  16 Dec 2011:
Vol. 334, Issue 6062, pp. 1507-1508
DOI: 10.1126/science.1216483

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The neuronal networks of the cerebral cortex implement complex cognitive functions like object perception or associative memory. The balance of excitatory and inhibitory inputs onto cortical neurons ensures the stability of such networks, but little is known about the mechanisms that control this process. On page 1569 of this issue, Vogels et al. (1) show that plasticity at inhibitory synapses can accomplish this.