An Exit Strategy for Measles Virus

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Science  23 Dec 2011:
Vol. 334, Issue 6063, pp. 1650-1651
DOI: 10.1126/science.1217378

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The causative agent of measles is one of the most infectious viruses known—each infected person can transmit the virus to 15 to 20 susceptible individuals. Identification of the cell adhesion molecule nectin-4 as an epithelial cell receptor for measles virus (1, 2) provides insight into how this high rate of transmission is achieved.