Technical Comments

Comment on “Dynamics of Dpp Signaling and Proliferation Control”

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Science  27 Jan 2012:
Vol. 335, Issue 6067, pp. 401
DOI: 10.1126/science.1210997

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Abstract

Wartlick et al. (Research Articles, 4 March 2011, p. 1154) reported that growth rates in the Drosophila wing disc correlate with increasing Dpp signaling levels, suggesting that the rate of Dpp increase determines the cell-cycle length. Contradicting their model, we found that cells in which the increase of Dpp signaling levels was genetically abrogated grew at rates comparable to those of wild-type cells.

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