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Science  17 Feb 2012:
Vol. 335, Issue 6070, pp. 867
DOI: 10.1126/science.335.6070.867-a

THERMAL CYCLER

The new G-Storm thermal cycler, GS482, embraces a sleek, black styling and features an enlarged screen to improve the user interface and experience. The new, cost-effective system is equipped with a number of enhanced features that increase the instrument's flexibility and functionality. The two independent 48-well blocks, both with sprung heated lids that adapt to both tubes and high profile 48-well plates within the GS482, enables two programs to be run independently or one program simultaneously on both blocks. Both of the GS482's thermal blocks feature two independent temperature control sensors and four peltier heating units to ensure accurate temperature control and uniformity across the block surface. Active Sample Cooling also ensures that samples are cooled until the heated lid reaches its target temperature.  Onboard software features a Program Wizard that can store up to 1,000 programs.

DISPOSABLE SYRINGE FILTERS

A new range of disposable syringe filters provide fast and efficient filtration of cell culture media. Manufactured in a Class 100000/ISO Class V clean room to ISO 9001:2008 and EN ISO 13485:2003 manufacturing standards ensures all Porvair syringe filters are free from DNA/RNA, DNAse/RNAse, and Pyrogen contamination. Stringent quality testing means each syringe filter performs reliably to specification. With three membranes to choose from an optimized syringe filter is available for most applications. Polyethersulfone membrane syringe filters exhibit a low affinity for proteins and extractables making them ideal for pre-filtration and filtration of buffers and culture media. The mixed Cellulose Ester membrane efficiently binds trace proteins making them the syringe filters of choice for filtration of aqueous solutions. Porvair's hydrophobic Nylon membrane offers excellent chemical compatibility across a wide pH range enabling it to be used for the filtration of either aqueous or organic solvents.

WESTERN BLOT STRIPPING SOLUTION

Based on G-Biosciences' popular Western ReProbe, this modified single component system is specifically formulated to dissociate and remove stubborn, high-affinity antibodies from membrane-bound proteins without destroying the antigenic-binding affinity. Western ReProbe PLUS saves time and money by eliminating the need to rerun gels and transfer processes and by offering you the ability to reuse Western blots. G-Biosciences' Western ReProbe PLUS eliminates the need for boiling, denaturants, or SDS. The membrane-bound protein is retained on the membrane and the matching antibodies are washed away. Once the antigen-antibody bonds are broken, the membrane-bound protein is free to accept new antibodies. G-Biosciences' Western ReProbe PLUS allows screening of the same blot with different antibodies, repeated analysis and correction of unsatisfactory blots with multiple probes, and comparison of phosphorylated and total protein on the same blot. Each 100 mL supply is sufficient for up to 30 standard size Western blots.

SAMPLE DRYING

Available for use with Genevac evaporators, Dri-Pure technology enables scientists to rapidly dry their samples without cross-contamination or loss of sample due to solvent bumping. Dri-Pure offers significant benefits to scientists, especially those working in synthesis and purification. Other methods of solvent removal tend to be very laborious or lead to unacceptable cross-contamination. Dri-Pure running on a Genevac evaporator gives smooth, controlled solvent removal in optimum time. The patented Dri-Pure technology is available for all current models of Genevac centrifugal evaporators, from the affordable EZ-2 through to the production-scale HT-24. Genevac's unique anti-bumping system works by carefully controlling the reducing pressure in the evaporation chamber in combination with an increase in rotor speed to achieve greater g-force. In addition, heat flow to the samples must be reduced during the pressure ramping stage. Dri-Pure achieves all this via the embedded instrument software and hardware that makes such an elegant solution easy to apply.

2-D CODED TUBES

Identifying your sample via a code on the tube can be done in a number of ways. However the most reliable in terms of long-term identification and tracking of samples is via a 2-D coding on the bottom of the tubes. Barcodes on Micronic 2-D Data Matrix and 2-D TraXis coded tubes are permanently laser-etched into the tube surface making them especially resistant to solvent attack and wear. Uniquely manufactured from a single component, the code in Micronic laser encrypted 2-D codes cannot fade or peel off even when subjected to repeated handling and freeze-thaw cycles. Because code clarity will remain unchanged throughout the lifetime of a Micronic 2-D coded tube, they offer unmatched secure sample traceability. Manufactured to industry-leading strict tolerances, the precision and tube-to-tube consistency of Micronic sample storage tubes maximizes uptime when used with automated handling systems.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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