News & AnalysisBiomedicine

Nanoparticle Treatment Reverses Cerebral Palsy in Rabbits

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Science  20 Apr 2012:
Vol. 336, Issue 6079, pp. 286
DOI: 10.1126/science.336.6079.286

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This week in Science Translational Medicine, researchers describe a treatment that restores nearly normal movement to rabbits with an induced form of cerebral palsy when given a few hours after birth. The therapy consists of an injection of an anti-inflammatory drug bound to nanoparticles that ferry the drug into the brain and deliver it to specific cells. The treatment's developers acknowledge it's not ready for clinical trials in humans, but they and others say the findings raise the possibility of a preventive treatment that could be given to high-risk infants soon after they're born.