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Comment on “Universality in the Evolution of Orientation Columns in the Visual Cortex”

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Science  27 Apr 2012:
Vol. 336, Issue 6080, pp. 413
DOI: 10.1126/science.1205737

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Kaschube et al. (Reports, 19 November 2010, p. 1113) argue that pinwheel density in three mammalian species follows a universal constant of π as predicted by their orientation-selective suppressive long-range connectivity model. We dispute their conclusions and suggest that a simple brain size–pinwheel density scaling law suffices in predicting the self-organized and disorganized orientation maps from primates to rodents.

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