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Response to Comment on “Universality in the Evolution of Orientation Columns in the Visual Cortex“

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Science  27 Apr 2012:
Vol. 336, Issue 6080, pp. 413
DOI: 10.1126/science.1206416

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Meng et al. conjecture that pinwheel density scales with body and brain size. Our data, spanning a 40-fold range of body sizes in Laurasiatheria and Euarchonta, do not support this conclusion. The noncolumnar layout in Glires also appears size-insensitive. Thus, body and brain size may be understood as a constraint on the evolution of visual cortical circuitry, but not as a determining factor.

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