News FocusTHE BIOLOGY OF GENOMES

Single-Cell Sequencing Tackles Basic and Biomedical Questions

Science  25 May 2012:
Vol. 336, Issue 6084, pp. 976-977
DOI: 10.1126/science.336.6084.976

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Summary

Because the cell is the basic unit of biology, researchers are increasingly trying to isolate, study, and compare them individually. At the meeting, four groups described new insights into how genomes generate diversity and what makes specific tumors resistant to treatment—all derived from sequencing DNA from individual human cells. Their reports sparked a lot of excitement about the potential of single-cell sequencing.