Policy ForumMedicine

Whole-Genome Sequencing: The New Standard of Care?

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Science  01 Jun 2012:
Vol. 336, Issue 6085, pp. 1112-1113
DOI: 10.1126/science.1220967

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Rapid advances in DNA sequencing technology have made whole-genome sequencing (WGS) both technically and economically feasible. WGS has been used with great effect in specific settings to clarify molecular diagnosis and even to guide therapy (1, 2). But are we ready for the routine use of WGS in the care of healthy individuals?