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Pay Now, Benefits May Follow

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Science  13 Jul 2012:
Vol. 337, Issue 6091, pp. 179
DOI: 10.1126/science.337.6091.179

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As a study known as HPTN 052 unequivocally proved last year, when people reduce the amount of HIV in their bodies, they are less likely to infect others. But for it to work, people, of course, have to learn that they are infected, seek care, and then take their medicine—and there's a steep drop-off between each of these steps, which collectively is called the "treatment cascade" (see p. 168). Now, an innovative and ambitious follow-on trial, dubbed HPTN 065, is taking place both here and in Washington, D.C., to see if it can build on its sister study.