News & AnalysisInfectious Disease

An Enterprising Time for HIV Vaccine Research

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Science  21 Sep 2012:
Vol. 337, Issue 6101, pp. 1446
DOI: 10.1126/science.337.6101.1446

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Summary

Teaching the immune system how to outwit a virus that itself survives by outwitting the immune system is a huge scientific hurdle—so much so that several leading AIDS vaccine developers have fled the field. But those who have stuck it out and the younger investigators who have joined them demonstrated at the AIDS Vaccine 2012 conference last week that persistence may finally be paying off. Several presentations offered new details about how HIV and the immune system interact, and others proposed novel vaccine design ideas. But the meeting's most important outcome was less tangible: a new commitment to better coordinate this high-stakes hunt.