News & AnalysisGenetics

Cancer Gene Data Casts Doubt on Popular Research Method

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Science  02 Nov 2012:
Vol. 338, Issue 6107, pp. 593
DOI: 10.1126/science.338.6107.593

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The online catalog PubMed contains more than 25,000 biology papers about Myc, a gene linked to aggressive cancers. But some researchers say that most of this work now needs to be reevaluated. They argue that Myc's cancerous effects are much broader than most people have assumed, and that a flawed experimental method may have thrown off a decade's worth of Myc research.