Functional DNA Origami Devices

Science  16 Nov 2012:
Vol. 338, Issue 6109, pp. 890-891
DOI: 10.1126/science.1231024

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DNA is central to the existence of all life on Earth and uniquely encodes the instructions for producing such life. But it has another set of remarkable properties shared by a much larger class of molecules, most of which are yet to be invented. These “chemically sequenced polymers” (CSPs) are built by adding distinct monomers one at a time and can be programmed in such a way as to assemble into arbitrarily complex and three-dimensional shapes. Nature is far ahead of us in the creation and utility of such molecules, but on page 932 of this issue, Langecker et al. (1) provide a glimpse of the structural precision and functionality they offer for programmed assembly.