PerspectiveMedicine

Cardiac Regeneration

Science  21 Dec 2012:
Vol. 338, Issue 6114, pp. 1549-1550
DOI: 10.1126/science.1228951

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Summary

In the United States, heart failure afflicts about 6 million people (1), costs $34.4 billion each year (2), and is now the single most common discharge diagnosis in those over 65 (3). Although enormous progress has been made in managing acute cardiovascular illnesses such as heart attacks, many patients go on to develop late sequelae of their disease, including heart failure and arrhythmia. Thus, the growing number of these patients in some ways represents a burden of our success. It also reflects the incomplete success of most current therapies, which mitigate and manage but do not cure the disease.