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Science  21 Dec 2012:
Vol. 338, Issue 6114, pp. 1638
DOI: 10.1126/science.338.6114.1638-a


The new KT 115 refrigerated incubator utilizes energy-efficient, state-of-the-art Peltier refrigeration technology to provide secure, accurate control. With comprehensive program functions, the unit offers a wide range of capabilities for incubating biological materials and guarantees reproducible results. Functional chamber volume is 3.7 ft3 (104 L), and the unit can run at temperatures down to 4° In contrast to a compressor, the Peltier technology, which is used exclusively for cooling, is vibration free and significantly reduces energy consumption. Conventional heating technology extends the operating life of the device, which can be conveniently decontaminated at its 100°maximum temperature. Proven APT.line preheating chamber technology ensures homogenous temperature conditions, as well as rapid heating and recovery times. Horizontal airflow from both sides of the chamber provides uniform temperature distribution, even when the unit is fully loaded. Temperature, set digitally, is accurate to a tenth of a degree and ensures effective and gentle incubation.


The Lightsheet Z.1 provides biologists with a new method of imaging dynamic processes in living organisms. Biologists can use the new microscopy system to observe the development of entire organisms over several days or more. The extremely low phototoxicity and the integrated incubation enable gentle imaging of specimens over hours to days. Lightsheet Z.1 works with an expanded light beam (the light sheet) that illuminates only a thin section of the sample, thus protecting the rest of the specimen. Images are captured at a 90°gle to the light sheet. Multiview imaging allows data acquisition from different viewing angles. These can be combined through mathematical algorithms into 3-D reconstructions and time-lapse videos. The light sheet system of the Lightsheet Z.1 uses a new type of optical concept that combines cylindrical lens optics with laser scanning. Users receive homogeneously illuminated optical sections of complete examination objects.


Designed for polymerase chain reaction (PCR), real-time PCR (qPCR), and Droplet Digital PCR (ddPCR) applications, the new PX1 PCR plate sealer and associated heat sealing films and foils remove human variability from plate sealing and prevent sample evaporation from impacting results. Poorly sealed microplates can permit sample evaporation, leading to large standard deviations in the number of quantification cycles (Cq) in qPCR experiments. The semi-automated design of the PX1 PCR plate sealer eliminates cumbersome manual sealing using heat and pressure to efficiently seal PCR plates, ensuring a perfect seal for uniform, reproducible PCR data. The PX1 PCR plate sealer integrates with many different PCR workflows including Bio-Rad's QX100 Droplet Digital PCR system, providing researchers with a complete, user-friendly workflow for ddPCR. The PX1 sealer is also ideal for researchers using small sample volumes, with which evaporation is a crucial concern.


A range of ready-to-use RNA samples now includes mRNA/micro-RNA tissue preparations and a large number of RNAs from mouse and rat development stages. Isolated from a variety of tissues—the biorepository of RNA samples covers over 30 species including human, animal, plant, insect, and cell line. Included within the biorepository are a wide range of normal tissue types as well as tissues of human disease conditions, from multiple donors, that are typically difficult to source. The range of total RNA isolated from major organs (embryonic stages to adult) includes RNA from individual brain regions that are difficult to obtain because of their size and anatomical complexity. Also available are a comprehensive collection of preparations from placenta, uterus, and embryo tissues at different stages of pregnancy plus a complete library of mammary gland specimens from non-pregnant, pregnant, lactating, and involuted animals.


A new robotic sample loading system, the HLW20 Well Plate Loader, is adaptable to most modern inverted microscopes. The simple, rugged, and compact HLW20 provides three independently controlled and encoded axes for rotational, vertical, and horizontal movement. Combine the HLW20 with a Prior ProScan stage for your inverted microscope and you have a system designed specifically for high-content screening applications with a capacity of 20 well plates (two racks of 10 each). The two stainless steel racks provided with each loader accommodate covered and uncovered well plates up to 19 mm in height. Sensors monitor the presence of well plate racks so that the system can be programmed to respond when racks are changed in the middle of a run. Upon detection of a newly installed well plate rack, the unique well plate detection system is able to automatically scan and identify the quantity of well plates in each rack, their location, and the barcodes (optional) and store that information for future use.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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