Research Article

Multiple Instances of Ancient Balancing Selection Shared Between Humans and Chimpanzees

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Science  29 Mar 2013:
Vol. 339, Issue 6127, pp. 1578-1582
DOI: 10.1126/science.1234070

Article Information

vol. 339 no. 6127 1578-1582

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History: 
  • Received for publication December 13, 2012
  • Accepted for publication February 1, 2013

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Author Information

  1. Ellen M. Leffler1,*,,
  2. Ziyue Gao2,*,
  3. Susanne Pfeifer3,*,
  4. Laure Ségurel1,4,*,
  5. Adam Auton5,,
  6. Oliver Venn5,
  7. Rory Bowden3,5,
  8. Ronald Bontrop6,
  9. Jeffrey D. Wall7,
  10. Guy Sella8,9,
  11. Peter Donnelly3,5,
  12. Gilean McVean3,5,§,
  13. Molly Przeworski1,4,8,,§
  1. 1Department of Human Genetics, 920 E 58th Street, University of Chicago, Chicago, IL 60637, USA.
  2. 2Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, IL 60637, USA.
  3. 3Department of Statistics, 1 South Parks Road, University of Oxford, Oxford OX1 3TG, UK.
  4. 4Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA.
  5. 5Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK.
  6. 6Department of Comparative Genetics and Refinement, Biomedical Primate Research Centre, Lange Kleiweg 139 2288 GJ, Rijswijk, Netherlands.
  7. 7Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143, USA.
  8. 8Department of Ecology and Evolution, 1101 E. 57th Street, Chicago, IL 60637, USA.
  9. 9Department of Ecology, Evolution and Behavior, Alexander Silberman Institute of Life Sciences, Hebrew University of Jerusalem, Jerusalem 91904, Israel.
  1. Corresponding author. E-mail: emleffler{at}uchicago.edu (E.M.L.); mfp{at}uchicago.edu (M.P.)
  1. * These authors contributed equally to this work.

  • Present address: Department of Genetics, Albert Einstein College of Medicine, New York, NY 10461, USA

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