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LIFE SCIENCE TECHNOLOGIES: An Expanding Color Palette for Biotechnology

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Science  12 Apr 2013:
Vol. 340, Issue 6129, pp. 220-222
DOI: 10.1126/science.340.6129.220


Think of any multiplexed biological technique. RT-PCR. DNA sequencing. Flow cytometry. Microscopy. All work on different principles. Yet all have one common factor: fluorescence. The ever-expanding variety of fluorescent molecules, nanoparticles, and proteins has expanded the palette, so to speak, of biological experimentation. The pages of research journals may be filled mostly with reds and greens, but today's researchers have literally dozens of hues available from which to choose. Such variety has expanded the spectrum of applications and instrumentation available to the research community. The future of fluorescence multiplexing has never seemed so, ahem, bright.