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Science  17 May 2013:
Vol. 340, Issue 6134, pp. 883
DOI: 10.1126/science.340.6134.883-a


Bio-Assembler Kits utilize magnetic levitation to culture cells in 3-D. Available in single-, six-, and 24-well configurations, the kits supply magnetic drivers, low-binding dishes/plates, and Nanoshuttle-PL solution in quantities and volumes appropriate for the kit's size. Nanoshuttle-PL solution delivers magnetic nanoparticles to cells. The magnetic driver that nests on top of the dish/plate then levitates the cells to create a 3-D environment. Using the Bio-Assembler Kits is as easy as performing standard 2-D cell culture plating and propagation. Culturing cells in 3-D facilitates rapid formation of floating yet connected scaffold-like structures with cell-cell interactions, thus providing a more accurate representation of tissue functionality in vivo. The process is compatible with virtually any cell type, including primary and stem cells, with any media type, with standard culturing protocols and diagnostic techniques, and is applicable to invasion studies and tissue engineering.


The easyPunch STARlet workstation is the first fully automated system integrating sample card punching and liquid handling into one easy workflow. The easyPunch STARlet system seamlessly integrates punching of GE Healthcare Whatman FTATM and DMPK sample collection cards with automated sample extraction, eliminating common bottlenecks in laboratory processes. The system minimizes human error and enables high throughput sample preparation for a variety of applications, such as forensic reference databasing, preclinical and clinical drug metabolism and pharmacokinetics (DMPK) studies, and toxicology studies. The easyPunch workstation is based on the Hamilton Robotics Microlab STARlet platform and features two special modules and robotic arms for transporting and punching paper cards. The samples are monitored by powerful tracking software to eliminate any chance of sample identification errors. The entire process is tracked using imaging recognition. Hamilton's proprietary software, based on industrial machine vision technology, provides complete control and monitoring of the punching process.


Magne Protein A Beads are designed for the purification of monoclonal and polyclonal antibodies from a range of diverse sources. These paramagnetic affinity beads offer a convenient method for achieving high purity and high recovery of immunoglobulins (Igs) from cell culture, ascites, and serum samples. They may also be used for high throughput antibody purification; antibody purification and concentration from small-volume or dilute source material; and for immunoglobulin depletion. Magne Protein A Beads are composed of iron encapsulated by macroporous cellulose, which results in low nonspecific binding and high-quality purification. Novel attachment chemistry is used to immobilize recombinant Protein A protein molecules all in the same orientation on the bead's surface. This orientation of attachment improves the functionality of the immobilized proteins. The beads' highly magnetic properties allow ease of handling as well as rapid and efficient protein capture, and can be used with a variety of magnetic stands.


HyClone HyCryo and HyCryo-STEM cryopreservation media enable researchers to maximize the preservation, recovery, and growth of post-thaw cells for general cell culture and stem cell applications. The new HyCryo media is a serum-free, animal component-free product intended for cryogenic preservation and storage of standard cell lines. Animal component-free assures the media is free of any human or animal nonhuman components to deliver better sample integrity and adaptability. Designed specifically for stem cell applications, HyCryo-STEM enhances cell recovery and post-thaw growth of pluripotent stem cells and neural progenitor cells. The serum-free formulation maintains differentiation potential and minimizes spontaneous differentiation of stem cells. HyCryo and HyCryo-STEM are designed to easily integrate into a researcher's existing cell culture workflow and processes. Researchers can simply add the HyCryo cryopreservation media directly to prepared cells and transfer to a Thermo Scientific Nunc Cryovial for sample integrity during freezing and long-term storage.


With the smallest diameter in the Kinetex family, the 1.3 μm UHPLC column delivers measurably better performance than conventional fully porous media on UHPLC equipment. The Kinetex core-shell family now includes four particle sizes, from 1.3 to 5 μm, providing separation solutions for virtually every chromatographic application and easy method transferability from UHPLC to HPLC to preparative-scale LC. With efficiency levels over 400,000 plates per meter, the Kinetex 1.3 μm represents a dramatic advancement in LC media technology. UHPLC users can now reach previously unavailable levels of sensitivity and performance, with the added benefit of easy method transferability and scalability to any of the three other Kinetex particle sizes. While fully porous sub-2 μm columns exhibit significant band broadening due to frictional heating as flow rate increases, the Kinetex particle morphology and packing technology help to reduce these and other effects to ensure high resolution and sensitivity over an extended linear velocity.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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