Science Webinar Series

Fluorescent Probes and Digital Imaging: Where We Are and Where We're Going

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Science  07 Jun 2013:
Vol. 340, Issue 6137, pp. 1247
DOI: 10.1126/science.340.6137.1247-c

Summary

The discovery of green fluorescent protein a half century ago heralded a new and explosive era in microscopy, forever changing the landscape for biology imaging. The ability to fuse a genetically encoded fluorescent probe to an almost-unlimited variety of proteins has enabled scientists to investigate signaling pathways and the movement of intracellular proteins in living cells with unprecedented detail, particularly when coupled with powerful widefield fluorescence and confocal microscopy techniques. Today, using the expanded selection of probes now available, researchers can even monitor multiple proteins simultaneously, in real time. This webinar will investigate how fluorescent protein probes are currently being utilized for live cell imaging, with a focus on applications in cancer research and where newly developed probes might take us in the near future.