Science Webinar Series

A Traveler's Guide to Next Generation Sequencing: Navigating the Sea of Genetic Variants

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Science  21 Jun 2013:
Vol. 340, Issue 6139, pp. 1479
DOI: 10.1126/science.340.6139.1479-c

Summary

Recent advances in technology and cost effectiveness of next generation sequencing has led to its progressively wider implementation in both research and clinical settings. The amount of data it produces, however, can be overwhelming—typically over three million variants per genome. The challenges for many researchers today are how to make sense of this huge volume of data in the context of the scientific question being asked, and how to identify those variants that provide meaningful and relevant information. In this webinar we will discuss current approaches to variant analysis and how they can be most effectively integrated into the next generation sequencing pipeline.