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The Dizzying Journey to a New Cancer Arsenal

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Science  28 Jun 2013:
Vol. 340, Issue 6140, pp. 1514-1518
DOI: 10.1126/science.340.6140.1514

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Carl June and others have engineered patients' own T cells to proliferate inside their bodies and seek and destroy cancer. In a small number of patients, the strategy has worked beyond the doctors' wildest expectations, although it doesn't work in everyone and there can be serious side effects. Now the researchers are on a quest to turn this experimental therapy into a treatment success.

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