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Engineered SIRPα Variants as Immunotherapeutic Adjuvants to Anticancer Antibodies

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Science  05 Jul 2013:
Vol. 341, Issue 6141, pp. 88-91
DOI: 10.1126/science.1238856

Article Information

vol. 341 no. 6141 88-91

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History: 
  • Received for publication April 8, 2013
  • Accepted for publication May 10, 2013

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Author Information

  1. Kipp Weiskopf1,2,3,*,
  2. Aaron M. Ring1,2,3,4,5,*,
  3. Chia Chi M. Ho1,2,3,4,5,
  4. Jens-Peter Volkmer1,2,3,
  5. Aron M. Levin4,5,
  6. Anne Kathrin Volkmer1,2,3,6,
  7. Engin Özkan4,5,
  8. Nathaniel B. Fernhoff1,2,3,
  9. Matt van de Rijn7,
  10. Irving L. Weissman1,2,3,7,*,
  11. K. Christopher Garcia2,4,5,*,
  1. 1Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  2. 2Ludwig Center for Cancer Stem Cell Research and Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
  3. 3Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
  4. 4Department of Molecular and Cellular Physiology, and Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  5. 5Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.
  6. 6Department of Obstetrics and Gynaecology, University of Dusseldorf, Germany.
  7. 7Department of Pathology, Stanford University Medical Center, Stanford, CA 94305, USA.
  1. Corresponding author. E-mail: kcgarcia{at}stanford.edu
  1. * These authors contributed equally to this work.

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