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Science  12 Jul 2013:
Vol. 341, Issue 6142, pp. 109
DOI: 10.1126/science.1242553

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How much risk can and should a journal tolerate in publishing papers that describe novel findings—that is, papers that could have a profoundly positive impact within and outside the scientific community if right, but could be broadly harmful by leading investigators in wrong directions if incorrect? I recently engaged a group of the Science editors in a lively discussion on this topic.