About the Cover

26 July 2013
Vol 341, Issue 6144

About the Cover

Cover image expansion

COVER Immunostained fluorescence microscopy image of memory engram–bearing cells (red) in the dentate gyrus of a mouse hippocampus (image width: 1.5 millimeters). These cells were genetically tricked to express the protein channelrhodopsin-2 during memory formation, thus becoming responsive to light stimulation. When the cells were activated by light, the mice simultaneously associated a genuine memory with an undesirable event (a foot shock) to create a new but false memory. See page 387. Image: Xu Liu and Steve Ramirez

About The Cover

Cover image expansion

COVER Immunostained fluorescence microscopy image of memory engram–bearing cells (red) in the dentate gyrus of a mouse hippocampus (image width: 1.5 millimeters). These cells were genetically tricked to express the protein channelrhodopsin-2 during memory formation, thus becoming responsive to light stimulation. When the cells were activated by light, the mice simultaneously associated a genuine memory with an undesirable event (a foot shock) to create a new but false memory. See page 387. Image: Xu Liu and Steve Ramirez