News & AnalysisInfectious Disease

Immune Suppressant Unexpectedly Boosts Flu Vaccine

Science  25 Oct 2013:
Vol. 342, Issue 6157, pp. 413
DOI: 10.1126/science.342.6157.413

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Summary

Experimental results are sometimes so paradoxical and downright weird that they open up never-imagined possibilities—and force researchers to rethink previous notions. Just such a finding surfaced in a study that gave mice a drug used to suppress the immune system and found that it bolstered the powers of an influenza vaccine. The drug's surprising impact on the immune system may offer a way to elicit more effective antibody responses from vaccines against myriad other diseases.