PerspectiveImmunology

Do T Cells Have a Cilium?

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Science  06 Dec 2013:
Vol. 342, Issue 6163, pp. 1177-1178
DOI: 10.1126/science.1248078

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Summary

It is claimed that all mammalian cells express a single cilia. Although the origin of this idea is unclear, it hasn't stopped immunologists from looking for cilia on hematopoietic cells. But is this a fruitless search? On page 1247 of this issue, de la Roche et al. (1) suggest that a cilia equivalent does exist in T lymphocytes, perhaps masquerading as a structure associated with T cell activation.