Table of Contents

03 January 2014
Vol 343, Issue 6166
  • Contents

    • This Week in Science

    • Editorial

    • Editors' Choice

    • Podcasts

    • Products & Materials

      • New Products

        A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.

    • News of the Week

    • News & Analysis

    • News Focus

      • Monumental Roots

        The great stone monuments of prehistoric Britain, including Stonehenge, were born in a wave of innovation that apparently began on a remote Scottish island.

    • Letters

    • Books et al.

    • Policy Forum

      • Promoting Transparency in Social Science Research

        Social scientists should adopt higher transparency standards to improve the quality and credibility of research.

    • Perspectives

    • Review

    • Research Articles

      • Fermi-LAT Observations of the Gamma-Ray Burst GRB 130427A

        Multiwavelength data from an extremely bright stellar explosion provide details of the physics of these violent events.

    • Reports

      • GRB 130427A: A Nearby Ordinary Monster

        Multiwavelength data from an extremely bright stellar explosion provide details of the physics of these violent events.

      • The First Pulse of the Extremely Bright GRB 130427A: A Test Lab for Synchrotron Shocks

        Multiwavelength data from an extremely bright stellar explosion provide details of the physics of these violent events.

      • First-Photon Imaging

        A computational imaging method based on photon timing enables three-dimensional imaging under low light flux conditions.

      • Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

        Tumor cells become resistant to targeted therapies by eliminating the gene encoding the drug target from extrachromosomal DNA.

      • A Neural Mechanism Underlying Mating Preferences for Familiar Individuals in Medaka Fish

        A particular class of neurons regulates female fish mating preference based on social familiarity.

      • Pregnenolone Can Protect the Brain from Cannabis Intoxication

        The universal precursor of steroid hormones acts as a negative allosteric modulator of cannabinoid receptors.

About The Cover

Cover image expansion

COVER Artist's conception of gamma-ray burst (GRB) 130427A, one of the brightest and longest-lived GRBs observed to date. GRBs such as this one occur when the core of a massive star runs out of nuclear fuel, collapses, and forms a black hole that drives a powerful jet of plasma traveling close to the speed of light. See pages 34, 38, 42, 48, and 51. Image: NASA/Fermi and Sonoma State University/Aurore Simonnet