Contents
Vol 343, Issue 6169
Special Issue
Exploring Martian Habitability
Introduction to Special Issue
Research Articles
Contents
This Week in Science
Editorial
Editors' Choice
Podcasts
- Science Podcast: 24 January Show
Listen to stories on the genome of a transmissible tumor, an update from Opportunity on Mars, and more.
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
News of the Week
- Around the World
In science news around the world, the comet-chasing European spacecraft Rosetta awakens from its 2.5-year nap, the U.S. Environmental Protection Agency estimates environmental damage from the proposed Pebble Mine in Alaska, and more.
- Newsmakers
Geophysicist Peter Molnar receives the Royal Swedish Academy of Sciences' Crafoord Prize in Geosciences, psychologists James McClelland and Elizabeth Spelke are honored with the U.S. National Academy of Sciences' inaugural Prize in Psychological and Cognitive Sciences, and statistical geneticist Joseph Terwilliger describes his experience touring North Korea with Dennis Rodman.
- Random Sample
Bored with the adult-dominated world of scientific editors and review panels, neuroscientist Robert Knight of the University of California, Berkeley, created Frontiers for Young Minds—a journal that enlists editors between the ages of 8 and 18 to evaluate kid-friendly articles written by neuroscientists.
News & Analysis
- Divulging DNA Secrets of Dead Stirs Debate
Genetic findings from research volunteers who die present a conundrum, and there's debate over how to handle that information.
- NIH Is Losing Its Funding Edge, 2014 Budget Suggests
The 2014 budget suggests that the National Institutes of Health is losing its place as first among equals when Congress has additional money to spend on research.
- Nano-Imaging Feud Sets Online Sites Sizzling
Researchers on both sides of a nanoscience dispute are claiming that recently published papers settle the debate in their favor, and one is charging his opponents with cyberbullying.
- Historic Patent on Embryonic Stem Cells Faces Scrutiny
A California advocacy group, Consumer Watchdog, is arguing in a top U.S. appeals court that stem cells isolated by James Thomson should never have been patented.
- A Lifeline for Syria's Science Exiles
As violence in Syria escalates and the regime increasingly targets academics, an international effort to support Syria's beleaguered scholars with visas, fellowships, and guest appointments is gaining momentum.
News Focus
- The Epigenetics Heretic
Michael Skinner's claim that chemicals can cause changes to gene expression that persist across multiple generations of animals has stirred excitement—and outrage.
- Selling America's Fossil Record
Paleontologists fear that a growing commercial fossil industry is swallowing up U.S. fossils and the data they hold.
Letters
Books et al.
- An Economist's Journey
Nordhaus offers an economic perspective of the challenges and possible responses to anthropogenic climate change.
- Bordering Fiction
Eggers portrays a world—in which an omnipotent social networking company encourages everyone to monitor everybody everywhere—that feels eerily everyday.
- Books Received
A listing of books received at Science during the week ending 17 January 2014.
Policy Forum
- Raw Personal Data: Providing Access
Donors should have access to raw data derived from their contributions to research or clinical repositories to increase personal choice and reciprocity.
Perspectives
- mRNA, Live and Unmasked
Visualization of mRNA dynamics in live neurons reveals its release from granules at synapses during neuronal plasticity.
- Hiding in Plain View—An Ancient Dog in the Modern World
The sequence of a transmissible cancer provides a snapshot of a dog from the distant past.
- Making the H-Cluster from Scratch
Spectroscopic data begin to elucidate the initial steps in the biosynthesis of the hydrogenase active site.
- Climate Effects of Aerosol-Cloud Interactions
Advances in satellite observations and model development are needed to disentangle the complex interactions of aerosols and clouds and their effects on climate.
- Extraordinary Color Vision
The compound eyes of mantis shrimps see color in a fundamentally different way from other animals.
- Lifting the Fog of Complexity
Combining surface- and bulk-sensitive experimental probes may help to solve the complexity underlying high-temperature superconductivity.
- The Fiery Side of HIV–Induced T Cell Death
A cytosolic protein that senses fragments of HIV-1 DNA triggers the death of uninfected CD4 T cells.
Review
Reports
- Charge Order Driven by Fermi-Arc Instability in Bi2Sr2−xLaxCuO6+δ
Surface and bulk measurements in bismuth-based cuprates agree and indicate a short-range charge order.
- Ubiquitous Interplay Between Charge Ordering and High-Temperature Superconductivity in Cuprates
Surface and bulk measurements in bismuth-based cuprates agree and indicate a short-range charge order.
- Imaging Dynamics on the F + H2O → HF + OH Potential Energy Surfaces from Wells to Barriers
A reaction is studied in fine detail by electron removal from a charged precursor to unveil and track a neutral intermediate.
- Strong Ground Motion Prediction Using Virtual Earthquakes
Ambient seismic noise helps predict the ground motion associated with future large earthquakes.
- Increased Dust Deposition in the Pacific Southern Ocean During Glacial Periods
A million-year-long marine sedimentary record of dust supply to the Pacific Southern Ocean reflects global climate.
- A Peptide Hormone and Its Receptor Protein Kinase Regulate Plant Cell Expansion
A signaling system important in the regulation of plant cell size during development is identified.
- A Different Form of Color Vision in Mantis Shrimp
Stomatopods use multiple photoreceptors to allow rapid color recognition rather than color discrimination.
- Risky Ripples Allow Bats and Frogs to Eavesdrop on a Multisensory Sexual Display
Calling frogs incidentally produce water ripples that are targeted by rival males and frog-eating bats.
- Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat
Endothelial cells control liver regeneration through paracrine hepatotropic and autocrine endotheliotropic mechanisms.
- Single β-Actin mRNA Detection in Neurons Reveals a Mechanism for Regulating Its Translatability
Imaging of β-actin messenger RNA (mRNA) in neurons reveals transient alteration of mRNA availability during synaptic plasticity.
- Visualization of Dynamics of Single Endogenous mRNA Labeled in Live Mouse
A transgenic mouse with fluorescently labeled endogenous β-actin mRNA permits single-molecule analysis in live cells.
- The HydG Enzyme Generates an Fe(CO)2(CN) Synthon in Assembly of the FeFe Hydrogenase H-Cluster
Vibrational spectroscopy traces the origin of carbon monoxide and cyanide ligands in the active site of di-iron hydrogenase enzymes.
- IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV
The intracellular sensor that triggers the death of human lymphoid CD4 T cells abortively infected with HIV is identified.
- Adaptation of Innate Lymphoid Cells to a Micronutrient Deficiency Promotes Type 2 Barrier Immunity
Vitamin A deficiency alters the balance of innate immune cells in the gut, promoting resistance to nematode infection.
- Transmissible Dog Cancer Genome Reveals the Origin and History of an Ancient Cell Lineage
An unusual tumor in dogs arose more than 10,000 years ago, and despite a huge mutational burden, its genome has remained stable.
