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Science  07 Mar 2014:
Vol. 343, Issue 6175, pp. 1159
DOI: 10.1126/science.343.6175.1159-a

GAS SORPTION ANALYZER

Quadrasorb evo Surface Area and Pore Size Analyzer is designed to satisfy busy laboratory needs for high analytical throughput, without sacrificing precision, flexibility, or cost-effectiveness. Up to four simultaneous and independent analysis ports remove the limitations of single dewar systems allowing samples to be started as soon as previous measurements are completed. A dedicated transducer has been provided for measurement of Po (adsorbate saturated vapor pressure), so that continually measuring Po does not slow down analysis capabilities. The new B.E.T. "QuickMode" provides high throughput industrial materials characterization labs the ability to process samples at dramatically improved speeds. Quadrasorb evo uniquely combines high throughput and analysis speed with unmatched flexibility. Dramatically improved analysis times have been accomplished through new proprietary features such as QuickMode and Dose Wizard. QuickMode allows the analysis of B.E.T. surface area measurements as much as 50% faster.

WIDE-FIELD HIGH-CONTENT SCREENING SYSTEM

The ImageXpress Micro XLS System is the latest improvement to Molecular Devices high-content screening portfolio. Developed as a single wide-field integrated system with unlimited hardware and software configurations, system-wide improvements offer enhanced speed and flexibility to both fixed-end point and time-lapse live-cell studies. The latest development combines leading-edge hardware components with the next generation MetaXpress Software in one package, to deliver greater throughput and performance. With a screening capability of >50,000 wells per day, the system allows for faster characterization of highly heterogeneous samples from large, diverse populations, and identification of rare subpopulations. The open modular design of the ImageXpress Micro XLS System allows for a variety of configurations, affording research labs total flexibility in addressing unique applications. The system includes environmental control, on-board liquid handling, and brightfield capabilities for label-free cellular monitoring over time-lapse experiments, eliminating the need for toxic nuclear stains in live-cell imaging.

LARGE SAMPLE VOLUMES CONCENTRATION

SampleGenie 3 technology used in conjunction with the Genevac Rocket Evaporator enables large sample volumes to be dried directly into vials, eliminating a number of time consuming sample handling steps and the attendant risk of errors. The new third generation SampleGenie enhances the exceptional capabilities of this unique sample concentration methodology through improved ease of use, enhanced evaporation performance, and reduced operational costs. Traditionally, protocols for concentration of chromatographic fractions has involved drying multiple fractions in an evaporator, resuspending pooled fractions into a single vial and then redrying before storage and analysis. Even with modern centrifugal evaporators such processes typically take two to three days to complete. The development of SampleGenie technology has been shown to enable samples in Genevac evaporators to be concentrated, without loss of volatile components, directly into a single GC or HPLC vial eliminating the need for reformatting of samples after drying.

SPE SAMPLE PREPARATION KIT

The Microlute SPE sample preparation starter kit contains everything needed to begin productive solid-phase extraction (SPE) sample preparation in a 96-well plate format, including two development filter plates and a popular C18 sorbent filter plate, 2 mL collection plates, disposable waste trays and, most importantly, the Microlute Acrylic Vacuum Manifold. The new starter kit offers all the advantages of SPE sample preparation in a convenient microplate format, capable of rapidly processing 96 samples in one run, repeatedly and precisely. All that is required for full operation is a suitable laboratory vacuum connection or pump. Handling samples as small as 150 μL, the Microlute SPE starter kit helps to increase analytical sensitivity by providing pre-injection cleanup and concentration. Two 'Development Microlute' plates in the kit are preloaded with eight different sorbents to aid method development. Once the most suitable sorbent has been identified, whole plates containing the chosen material can be ordered for use with the Microlute system.

LABEL-FREE PLATFORM

The Octet HTX system is the new flagship member of the Octet line of label-free interaction analysis systems. The Octet HTX system addresses the acute industry need for increased analysis speed and sample throughput when characterizing large numbers of therapeutic candidates. Octet systems provide unique insights into drug-target binding interactions, insights that are used to fine-tune the affinity and specificity of drug molecules. The Octet HTX instrument performs kinetic analysis of up to 96 binding interactions simultaneously, a capability offered by no other standalone label-free platform. The system offers dramatic time savings for researchers studying large panels of drug candidates, and provides innovative data analysis tools for developers of monoclonal antibodies and other biotherapeutic entities. In addition, the Octet HTX performs full 96-well plate determinations of protein concentrations in as little as two minutes. The HTX system was engineered for speed while maintaining peak performance, and will directly address critical bottlenecks in the drug development process.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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