News & AnalysisSTEM CELLS

Irreproducibility Dogs New Reprogramming Method

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Science  21 Mar 2014:
Vol. 343, Issue 6177, pp. 1299-1300
DOI: 10.1126/science.343.6177.1299

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Since January, scientists around the world have attempted to reproduce a surprising stem cell finding that claimed that simply stressing adult cells could turn them into powerful stem cells, called stimulus-triggered acquisition of pluripotency (STAP) cells, which resemble those found in early embryos. No one has reported success. Now, Science has learned that some of the labs involved in producing the two papers describing the work had not attempted to reproduce the technique before the papers were published. Only two of the labs involved in the papers say they have been able to generate STAP cells.