Neurons' New Birthday

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Science  28 Mar 2014:
Vol. 343, Issue 6178, pp. 1407
DOI: 10.1126/science.343.6178.1407-a

Mice generate new olfactory neurons throughout adult life. Although humans seem not to generate new olfactory neurons in adulthood, the site at which those new neurons are born, the lateral ventricle wall, seems to generate neurons in both mice and humans. Ernst et al. use carbon-14 dating from nuclear bomb test exposures to compare the birth dates of neurons to the birth dates of the people being analyzed. The results show that unexpectedly, some striatal neurons are generated after birth. Calculations indicate that neurogenesis from the lateral ventricle wall in the adult human supplies interneurons in the striatum.

Cell 156, 1072 (2014).

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