NewsBreast Cancer

The 'Other' Breast Cancer Genes

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Science  28 Mar 2014:
Vol. 343, Issue 6178, pp. 1457-1459
DOI: 10.1126/science.343.6178.1457

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First there were the BRCA genes. Now, dozens or more breast cancer genes have been unmasked. But unlike BRCA1 and BRCA2, the risk these genes pose is uncertain. And that leaves doctors and genetic counselors in a bind. With understanding so limited, is information on these genes even helpful? Should women with a family history of breast cancer be tested for them? And what do you tell them if the test comes back positive?