New Products

See allHide authors and affiliations

Science  29 Aug 2014:
Vol. 345, Issue 6200, pp. 1080
DOI: 10.1126/science.345.6200.1080-a

Biochemistry Analyzers

The YSI brand 2900 Series Biochemistry Analyzers constitute an essential part of many stages of bioprocessing and life sciences applications due to their ability to accurately and rapidly monitor and control fermentations and cell cultures. YSI biochemistry analyzers offer both offline and online analysis of critical samples for companies that manufacture vaccines, small molecules, alcoholic beverages, chemicals, and biofuels. The YSI 2900 Series includes the 2900, the 2950, and the recently launched 2900M biochemistry analyzers. YSI biochemistry analyzers are able to measure, monitor, and control processes accurately, easily, and quickly (under one minute) due to their innovative biosensor technology. To obtain high product yields in biotech or pharmaceutical applications, the metabolism and health of the cell cultures have to be assessed regularly. And there's a crucial need to monitor key nutrients and byproducts levels, and to adjust feed rates on the bioreactor accordingly.The YSI 2900 Series biochemistry analyzers offer accurate, rapid, and reproducible methods to measure and monitor the process.

Microarray Screening Device

The b-screen label-free microarray screening device is an analysis tool for microarrays in the standard microscope format allowing the detailed studies of biomolecular interactions. Kinetic data can be obtained for almost any kind of biomolecular interaction such as for protein/protein, peptide/protein, and small molecules/protein. b-screen provides a label-free readout of up to 10,000 spots per square centimeter. It utilizes a precise and automated microfluidics system for incubation of the microarray with the sample of interest. The device can be used with multiple array layouts (highly scalable), uses glass or plastic type substrates, and is compatible with almost any common microarray printer. The high throughput analysis is characterized by a high time resolution (no scanning) at low noise of the optical readout. No fluorescence labels are needed, which leads to assay conditions as close as possible to the in vivo situation combined with minimal sample pretreatment and minimized reagent consumption.

Mass Spectrometer Control Module

A new control module for the expression compact mass spectrometers (CMS) includes both digital control of the detector and digital data acquisition of the detector signal. It also allows performing all service operation necessary for the detector from the Device Monitor software window. Clarity Chromatography Software provides seamless integration of expression CMS with a wide range of high-performance liquid chromatography (HPLC) systems that are already controlled by Clarity. Clarity MS Extension greatly extends Clarity capabilities. Clarity is able to evaluate spectral data from MS detectors together with data from conventional HPLC detectors (including quantification) and add the third dimension for data analysis. Clarity Chromatography software can provide interactive spectral analysis, peak purity analysis and compound identification that is based on a spectral library search. The extension is prepared to function with single quadrupole mass spectrometer (MS) and time-of-flight MS detectors. Clarity is highly regarded for its intuitive approach, excellent performance, cost-effectiveness and proficient technical support.

Metabolic Microplate Assay

The XFe96 Spheroid Microplate is a unique 96-well plate featuring geometry that enables functional, metabolic measurements of individual spheroids for the study of three-dimensional cell culture, which more closely mimics in vivo conditions. Of particular importance for tumor studies, the real-time metabolism of multicellular spheroids can now be analyzed and used for evaluating the metabolic response to therapeutic agents. Using the XFe96 Spheroid Microplate and the XFe96 Extracellular Flux Analyzer, scientists can obtain sensitive and reproducible data from individual spheroids with high specificity. The XFe96 Extracellular Flux Analyzer simultaneously measures the two major energy-producing pathways within the cell—mitochondrial respiration and glycolysis—in a microplate, in real time. The XFe96 Analyzer and Stress Test Kits standardize the measurement of mitochondrial function and glycolysis. The addition of the XFe96 Spheroid Microplate further advances the study of cell metabolism. The XFe96 Spheroid FluxPak contains six cartridges, six microplates, and calibrant.

Cell Sorting and Sub-Micron Particle Detection

The MoFlo Astrios EQ is a six-way jet-in-air sorter, which delivers patent pending enhanced dual forward scatter (eFSC) technology for simultaneous sorting and detection of particles from 200 nm to 30 m in diameter. The instrument sets a new standard for flow cytometry core facilities, delivering high-speed cell sorting and microparticle detection in a single package. Featuring detailed and precise forward scatter resolution, beadless drop sample handling and increased biosafety, Astrios EQ meets a range of analysis needs. Intellisort II, the world's first and only beadless drop-delay technology, eliminates the need for bead-based drop-delay routines. This alleviates the requirement to remove sterile samples during drop-delay recalculation due to nozzle blockages and ensures uninterrupted sort sterility. Intellisort II's ability to maintain droplet breakoff for uninterrupted aseptic sorting helps to preserve sort integrity. A broad standard laser palette provides more wavelength choices than is found in most standard cuvette-based systems.

Inverted Microscope

The Leica DMi1 enables cell biologists to check and document cell and tissue cultures within seconds. Its ease-of-use and efficient operation make it an excellent choice for routine laboratory work as well as for training. Combining high performance and affordability, the Leica DMi1 is equipped with LED illumination that provides constant color temperature with up to 20 years life-time. The convenient two-hour auto-off function helps reduce energy costs. For the finest visualization of cells cultured in a variety of containers, phase contrast is available in addition to brightfield illumination. The 40–50 mm or 80 mm working distance means that a wide variety of culture containers like flasks, dishes, or multiwell plates can be used on the fixed stage. An optional object guide with different kinds of holding frames is available to securely and reliably hold and move laboratory vessels during observation and documentation.

  • Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

Navigate This Article