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Science  05 Sep 2014:
Vol. 345, Issue 6201, pp. 1195
DOI: 10.1126/science.345.6201.1195-a

Automated Sample Storage

The BiOS M and L are two compact, high-density automated systems designed to fit into existing laboratories that require ultralow-temperature storage of sensitive biological samples. These flexible, energy-efficient, and scalable systems ensure the viability of 100,000 to over one million long-term samples. Laboratories depend on biobanks to supply well-annotated, high-quality samples that are collected within appropriate ethical parameters and under infallible conditions. The BiOS M and L are ideal for forensic applications, and medium-sized research and clinical repositories. Samples are held in labware that is both tracked and picked automatically without human intervention, thus avoiding the risk of inadvertent warming and degraded sample integrity. By adding smaller configurations of our high-capacity BiOS -80°C storage system more labs have access to state-of-the-art sample storage within steps of their sample preparation and analysis stations. This reduces the likelihood that results may be compromised.

NGS Library Prep

MagSi-NGSPREP is a magnetic, bead-based tool that offers an efficient solution for DNA cleanup and size selection in next generation sequencing (NGS) applications. MagSi-NGSPREP supports all standard DNA clean-up protocols encountered during Next-Gen library preparation, including the classical one-sided and two-sided "solid phase reversible immobilization" size selection protocols. The simple and flexible protocols employed using MagSi-NGSPREP can be adjusted to your specific application and NGS platform. MagSi-NGSPREP can be used manually but is also easy to automate for high throughput processing. Using MagSi-NGSPREP, DNA fragments are bound directly onto the surface of the magnetic beads, leaving unincorporated nucleotides, primers, primer dimers, and other contaminants in solution. Following this the DNA fragments are eluted with low salt buffer or reagent grade water. The technology for binding of DNA fragments onto the applied magnetic nanoparticle surface does not require use of any hazardous chaotropic buffers.

Water Purification System

ELGA LabWater's PURELAB flex 5 and 6 are all-in-one, fully automated, standalone water purification systems for ion chromatography built to eliminate the need for eluent monitoring and water refilling. Delivering volumes up to 10 L per day, the PURELAB flex 5 is perfect for general use labs, while the PURELAB flex 6 is optimized for usage above 10 L per day. A closed architecture avoids eluent contamination. The multi-usage systems deliver high-quality water throughout the workflow, including eluent generation, system rinsing, and general laboratory applications. They also reduce eluent preparation time compared to using bottled water. With these benefits, PURELAB flex 5 and 6 offer a unique "switch on and walk away" solution for ion chromatography, enhancing detection accuracy through improved water stability and purity.

Magnetic Bead Immunoprecipitation System

The SureBeads Magnetic Bead System provides researchers with a faster and easier alternative to agarose beads for immunoprecipitation (IP). Benefits include: reduced antibody consumption and sample loss, very low nonspecific binding, and optimized IgG binding capacity. Researchers have traditionally used agarose beads to precipitate and enrich proteins prior to Western blotting or mass spectrometry. Magnetic beads are an attractive alternative to agarose beads for several reasons, chiefly ease of use at the bench: magnetization is faster and more convenient than centrifugation for sample precipitation and washing steps. More researchers would likely switch to magnetic beads if they were not significantly more expensive than agarose beads. With the launch of the SureBeads System, scientists now have access to a high-performance, cost-effective magnetic bead system. SureBeads Protein A & G Conjugated Magnetic Beads are designed to work with the SureBeads 16-Tube Magnetic Rack.

Spectrophotometer

SimpliNano is a simple-to-use microvolume spectrophotometer for straightforward concentration and purity measurements of nucleic acids and proteins. There are no moving parts in SimpliNano, making it reliable and easy to maintain, with excellent instrument reproducibility. The fixed path length means samples can be added and removed without the need for time-consuming calibration. Small volumes down to one microliter can be analyzed by pipetting directly into the built-in sample port, reducing sample loss, and eliminating the need for cuvettes or other sampling tools. Samples can be recovered or wiped away after measurement and the sample port is compatible with a variety of common laboratory chemicals. SimpliNano is programmed with a range of methods for conveniently measuring nucleic acid concentrations at 260 nm and proteins at 280 nm as well as purity. The spectrophotometer offers freedom of choice as it can be operated through its direct user interface, or through a PC with optional Datrys software.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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