Review

Human cognitive aging: Corriger la fortune?

Science  31 Oct 2014:
Vol. 346, Issue 6209, pp. 572-578
DOI: 10.1126/science.1254403

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Abstract

Human cognitive aging differs between and is malleable within individuals. In the absence of a strong genetic program, it is open to a host of hazards, such as vascular conditions, metabolic syndrome, and chronic stress, but also open to protective and enhancing factors, such as experience-dependent cognitive plasticity. Longitudinal studies suggest that leading an intellectually challenging, physically active, and socially engaged life may mitigate losses and consolidate gains. Interventions help to identify contexts and mechanisms of successful cognitive aging and give science and society a hint about what would be possible if conditions were different.

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