Review

Advances in skin grafting and treatment of cutaneous wounds

+ See all authors and affiliations

Science  21 Nov 2014:
Vol. 346, Issue 6212, pp. 941-945
DOI: 10.1126/science.1253836

You are currently viewing the abstract.

View Full Text

Abstract

The ability of the skin to repair itself after injury is vital to human survival and is disrupted in a spectrum of disorders. The process of cutaneous wound healing is complex, requiring a coordinated response by immune cells, hematopoietic cells, and resident cells of the skin. We review the classic paradigms of wound healing and evaluate how recent discoveries have enriched our understanding of this process. We evaluate current and experimental approaches to treating cutaneous wounds, with an emphasis on cell-based therapies and skin transplantation.

View Full Text