Science Webinar Series

Antibody validation roundtable
specificity + sensitivity + reproducibility = validation

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Science  28 Nov 2014:
Vol. 346, Issue 6213, pp. 1131
DOI: 10.1126/science.346.6213.1131-c

Summary

Concerns about incorrectly or insufficiently characterized antibodies employed in biomedical research have been raised by recent reports of nonreproducible research studies. Reproducibility issues have resulted in loss of time, resources, and scientific reputation, with publication retractions occurring in certain cases. This webinar will highlight the challenges surrounding how antibody specificity affects reproducibility in biomedical research and introduce viewers to the key requirements for proper antibody validation. Panelists, including a journal editor, an academic researcher, a pharmaceutical company investigator, and an antibody supplier will share their views and unique perspectives. This forum is intended to serve as one step along an ongoing path toward building consensus on best practices for antibody validation and possible guidelines for reporting of antibody-based data in research manuscripts. By registering in advance for this webinar you can pose your specific questions for consideration by the panelists.