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Comment on “A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity”

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Science  06 Feb 2015:
Vol. 347, Issue 6222, pp. 621
DOI: 10.1126/science.1255437

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Sayou et al. (Reports, 7 February 2014, p. 645) proposed a new model for evolution of transcription factors without gene duplication, using LEAFY as an archetype. Their proposal contradicts the evolutionary history of plants and ignores evidence that LEAFY evolves through gene duplications. Within their data set, we identified a moss with multiple LEAFY orthologs, which contests their model and supports that LEAFY evolves through duplications.

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