PerspectiveGene Expression

Statistics requantitates the central dogma

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Science  06 Mar 2015:
Vol. 347, Issue 6226, pp. 1066-1067
DOI: 10.1126/science.aaa8332


  • Control of protein expression.

    The charts show the percent contributions of the variance in the rates of each step in gene expression to the variance in protein abundance for 4212 genes (from a mouse cell line). The left chart shows estimates from (5); the right chart shows estimates from (1) that take into account stochastic and systematic errors in the abundance data of (5).

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