Policy ForumVaccine Testing

Ebola and beyond

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Science  03 Apr 2015:
Vol. 348, Issue 6230, pp. 46-48
DOI: 10.1126/science.aaa3178

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Many epidemic-prone infectious diseases present challenges that the current West African Ebola outbreak brings into sharp relief. Specifically, the urgency to evaluate vaccines, initially limited vaccine supplies, and large and unpredictable spatial and temporal fluctuations in incidence have presented huge logistical, ethical, and statistical challenges to trial design.